DEFINITION OF TERMS

ante - before
antepartum - time before delivery
prenatal - time before death
gravida - any pregnancy regardless of duration, including the present one
nulligravida - women who has never been pregnant
para - number of births after 20 weeks gestation regardless of whether the infants were born alive 
           or dead (multifetal pregnancies are considered single para)
primigravida - pregnant for the first time
multigravida - a woman who is in her second or subsequent pregnancy
nullipara - woman who has not given birth at more than 20 weeks gestation
primipara - woman who has given birth to a fetus (dead or alive) that has reached 20 weeks gestation
multipara - woman who has given birth two or more times at more than 20 weeks gestation
still birth - fetus born dead after 20 weeks gestation
abortion - pregnancy that terminates before the fetus reaches 20 weeks but before full term
post-term birth - pregnancy that terminates 2 weeks after the expected date of birth or 42 weeks of
           gestation


OBSTETRIC HISTORY

GTPALM 
          - method that is commonly used for recording (using symbols) a woman's pregnancy history
          - provides a systematic, quick system to indicate not only the number of pregnancies the 
            woman has had but also the outcomes, which can be shown using a shorthand method

                     G - gravida
                     T - term pregnancies
                     P - premature births
                     A - abortions
                     L - number of living children
                    M - multiple gestations

Example:

          A pregnant woman who has 4 living children all single births, and who has had no preterm births and no abortions.

          GTPALM: 5-4-0-0-4-0


DETERMINATION OF DATE OF BIRTH

Naegels' Rule - method for obtaining an estimated date of delivery

          To calculate:
          a. Identify the last normal menstrual period
          b. Count backwards 3 months
          c. add 7 days

Example:

          LNMP : October 18
          EDB : July 25

          The average duration of pregnancy is approximately 280 days. This period is calculated in 28-day months called lunar months. 10 lunar months (40 weeks, 280 days) in a full-term pregnancy.


SIGNS OF PREGNANCY

1. Presumptive - may suggest pregnancy
2. Probable - woman is likely pregnant
3. Positive - gives definite evidence that the woman is pregnant

Presumptive Signs of Pregnancy
          - nausea and vomiting
          - urinary frequency
          - fatigue (may be excessive)
          - breast tenderness and changes
          - uterine enlargement
          - quickening: feels tight, fluttery movements of fetus, at about 18-20 weeks of pregnancy usually
            caused by gas movements within bowel or increased peristalsis

Probable Signs of Pregnancy

Uterine enlargement
Linea Negra - changes in skin pigmentation that appears on the abdomen, nipples and areola of the
          breast caused by hormonal increase
Goodell's Sign - softening of the cervix
Hegar's Sign - softening of the lower portion of the uterus
Chadwick's Sign - bluish-purple discoloration of vaginal mucous membrane
Piskacek's Sign - enlargement and softening of the uterus
Ballottement - reboundign of fetus in amniotic fluid felt by examiner during pelvic examination
Braxton-Hick's Contraction - painless, irregular uterine contractions, felt by women as tightening across 
          the abdomen
Positive pregnancy tests - presence of hCG in the uterine/plasma
Uterine souffle - soft, blowing murmur auscultated over the uterus after 4th month of pregnancy

Positive Signs of Pregnancy

1. Fetal heart sounds heard
          - audible at 10-12 weeks gestation through Doppler UTZ 
          - audible at 16-20 weeks gestation by fetoscope
          - normal FHR: 120-160 bpm
2. Fetal movements palpated by examiner
3. Fetal outline visualized by ultrasound


REPRODUCTIVE SYSTEM CHANGES OF PREGNANCY

a. Uterus
          - increase in length, width, depth, weight and volume
          - Braxton-Hick's contraction occurs intermittently throughout pregnancy and can be felt by the 
            woman by the 4th month
          - after 20 weeks' gestation, fundal height in centimeters approximates the weeks of pregnancy
            up to 36 weeks

b. Cervix
          - stimulated by estrogen, becomes vascular and edematous
          - endocervical glands secrete thick mucous plug which seals the endocervical canal and 
            prevents contamination
          - Goodell: softening of the cervix, results from cervical vascularization

c. Ovaries
          - do not produce ova
          - corpus luteum produces hormones (estrogen and progesterone) for the first 16 weeks of 
            pregnancy and then decrease in size

d. Vagina and External Genitalia
          - increase vascularization causes tissue to thicken and soften
          - vaginal discharge tends to be thick, white and acidic

e. Breasts
          - increase in size and becomes more nodular due to glandular hyperplasia and hypertrophy
          - nipple and areola darken, superficial veins become more prominent
          - colostrum may leak or be expressed from the breast during the last 3 months of pregnancy

striae - stretch marks
colostrum - thin, pale, yellow, serous fluid excreted in the breasts during the first few days after 
          parturition


RESPIRATORY SYSTEM CHANGES
          - diaphragm elevates and the substernal angle increases due to an enlarging uterus
          - displacement causes shortness of breath
          - increase RR by about 20 cpm


CARDIOVASCULAR SYSTEM CHANGES
          - heart is displaced upward to the left and forward
          - as the uterus enlarges, pressure on blood vessels increase and slows circulation which may 
            lead to edema and/or varicosities of the legs, vulva and rectum
          - pressure of the enlarged uterus on the vena cava causes supine HPN syndrome during 2nd tri


GASTROINTESTINAL SYSTEM CHANGES
          - gastric acidity decreases 
          - heartburn and flatulence may also be manifested due to decreased gastric acidity
          - bloating and constipation may occur due to delayed gastric emptying and decreased intestinal
            motility


URINARY SYSTEM CHANGES
          - urine output increases while urine specific gravity decreases
          - urinary stasis and UTI may occur due to pressure on the ureters and urethra from the growing 
            fetus
          - bladder capacity increases to 1500 mL
           - urinary frequency occurs in the first and third trimester dues to pressure from enlarged uterus


INTEGUMENTARY SYSTEM CHANGES
          - pigmentation changes occur in the areola, nipple, abdomen, thighs and vulva
          - facial chloasma (mask of pregnancy) and vascular spider nevi may develop
          - activity of sebaceous and sweat glands may increase


SKELETAL SYSTEM CHANGES
          - symphysis pubis may separate
          - lumbodorsal spine curve is increased during the third trimester commonly producing low back
            pain
          - lordotic posture is evident (pride of pregnancy)


METABOLIC CHANGES
          - accelerate to 20%
          - average weight gain is 24-30 lbs
          - increase water retention during pregnancy to support the increase in blood volume and to serve
            as a ready source of nutrients for the fetus


ENDOCRINE SYSTEM CHANGES
          - rise in thyroxine (T4)
          - increase parathyroid hormone production 
          - APG increases secretion of prolactin, responsible for lactation
          - PPG releases oxytocin, producing uterine contraction
          - PPG releases oxytocin and vasopressin to promote vasoconstriction 
          - pancreas increases production of insulin
          - placenta is the endocrine gland of pregnancy, secretes hormones of pregnancy - hCG, estrogen,
            progesterone, hPL and relaxin


          

 
fertilization - the union of sperm and ovum
                      normally takes place in the outer third of the uterine (fallopian tube) and usually occurs within 36 hours of ovulation
zygote - organism formed by the union of two gametes (sperm and ovum)


FETAL DEVELOPMENT: 3 STAGES


1. Pre-embryonic stage
          - encompasses the first 14 days of conception
          - embryonic membranes are established
          - 3 primary germ layers of embryo

                    a. Ectoderm - nervous system, skin, hair and nails, sense organs
                    b. Mesoderm - supporting structures of the body, muscles, bones and connective tissues
                    c. Endoderm - digestive system, respiratory tract


2. Embryonic Stage
          - begins during the 3rd week after conception
          - continue until the embryo reaches a crown-to-rump length of 3 cm at about the 8th week

          - this time, embryo is referred to fetus

          - the differentiation of tissues into organs and development of main external features occur



3. Fetal Stage
          - begins 8-10 weeks after conception and continues until the end of pregnancy

          - fetus is fully developed structurally 

          - fetus receives oxygen and excretes carbon dioxide through placenta
          - 3 shunts in fetal circulation that must close at birth:                    a. Ductus arteriosus
                    b. Ductus venosus
                    c. Foramen ovale
          - usually at 12th week of gestation, external genitalia are developed


EMBRYONIC AND FETAL SUPPORT STRUCTURES

1. Corpus luteum
          - supplies most of the estrogen and progesterone in the first 2 gestational months before
            placenta is developed 
          - supplying such hormones is essential for sustaining the uterine endometrium and preventing
            menstruation

2. Decidua
          - endometrium becomes the decidua following conception and implantation
          - protects and nourishes embryo
          - composed of 3 layers:
                    a. Decidua basalis
                    b. Decidua capsularis

                    c. Decidua vera



3. Placenta
          - begins to function by the 4th week of gestation by the 14th week, it is complete, independently

          - transmits nutrients and oxygen to the fetus and removes waste and carbon dioxide by diffusion 
          - also known as endocrine gland of pregnancy

          a. Estrogen
              - stimulates the growth of the uterine muscle and glandular epithelium
              - stimulates uterine growth and uteroplacental blood flow
              - enhances growth of all organs and ensures nourishment of developing tissue
              - indicates placental function, fetal maturity and fetal well-being

          b. Progesterone
              - promotes thickening and increased viscosity of cervical mucous (mucous plug) to protect the
                fetus from invading bacteria
              - decreases motility of the oviducts and uterus
              - stimulates growth of glandular breast tissue in preparation for lactation
              - maintain uterine lining for implantation
              - relaxes uterine smooth muscle

          c. HCG
              - partly responsible for maintaining the corpus luteum 
              - first indicator of a positive pregnancy
              - monitored to determine fetal well-being

          d. Human Placental Lactogen
              - human chorionic somatotropin
              - stimulates maternal metabolism
              - facilitates glucose transportation across the placenta
              - stimulates breast development to prepare for lactation

4. Membrane and Amniotic Fluid
          - 2 membranes form and protect and support the embryo
                    a. Chorion - outside embryonic membrane
                    b. Amnion - innermost membrane

   Amniotic fluid - contained within the amnion

          - fluid volume: 500-1000 mL
          - function: protects the embryo and the fetus, controls temperature, supports symmetrical growth,
            prevents adhesion to amnion, allows embryo or fetus to move within the amniotic cavity

5. Umbilical cord 
          - at term, it is 30-90 cm long and 2 cm in diameter
          - contains 2 arteries and 1 vein (AVA)
          - 2 arteries carry blood from the fetus to the placenta
          - 1 vein returns blood and nutrients to the fetus
          - normally inserted at the center of the placenta
          - contains Wharton's jelly, which is a connective tissue that prevents compression of the blood 
            vessels

          


      
 
These are few of my notes. I hope it can help you.

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